In the skin, melanocytes are situated on the basal layer which separates dermis and epidermis. One melanocyte is surrounded by approximately 36 keratinocytes. Together, they form the so-called epidermal melanin unit. The melanin produced and stored inside the melanocyte in the melanosomal compartment is transported via dendrites to the overlaying keratinocytes. Mulberry extracts can be incorporated  into skin-whitening products.

The compound attributed to lighten the skin is .arbutin, a form of hydroquinone that inhibits melanin  release  by  suppressing  the  tyrosinase enzyme. The active constituents of mulberry contained flavonoids, alkaloids, steroids, coumarins, with the significant hypoglycemic, hypolipidemic, antihypertension, anti-oxidation, anti-inflammatory, anti-bacterial, anti-tumor and immunomodulatory activities.

Properties

 

  • Skin lightening
  • İnhibition of melanin production
  • Increases skin density (as a result of increased collagen synthesis
  • Smoothes skin and reduces appearance of wrinkles
  • Antioxidant and Antimicrobial Activity

Pratical Hints

Product Name

 

 

FULL BRIGHT EX.

 

INCI Name

 

Propanediol

Morus Alba Fruit Extract

Daucus Carota Sativa Root Extract

Citrus Paradisi Fruit/Seed Extract

Dosage

 

 

Recommendations: 2-3%

Can be used in 1%-10% in various formulation type

Precautions  

Use freely in any step to make any formulations

Storage

 

 

Storage period with original packing at general storing condition (at room temperature, normal dry condition)

Store in cool place. Keep container tightly closed in a dry and well-ventilated place

 

Specification

 

 

Apparance                             Transparent liquid to slightly turbid

Odor                                        Characteristic

Solubility                               Soluble in aqueous solutions

pH                                        3.0-5.5

Specific Gravity                    1.000-1.150 at 20 °C

Microbial Analysis                 Less than 100 CFU per gram

Recommended Applications & Use Levels

Applications: For use in skin care products, especially those for ageing, anti-wrinkle and mature skin and  atopic dermatitis.

 

Recommended use levels:  2-3%

References:

1- Gug K. Physiological and Whitening Effects of  Morus alba  Extracts. J. of the Chosun Natural Science. Vol. 5, No. 1 (2012) pp. 46—52.

2- Natarajamurthy SH, Dharmesh SM . Protective effect of Daucus  carota against UV-DMBA induced skin cancer in mice. Chem Biol Interact. 2014 Aug 5;219:48-56

3- Kiefer S  et all. Citrus Flavonoids with Skin Lightening Effects – Safety and Efficacy Studies. Sofw Journal.12,2010.

4- Safety Assessment of Citrus Fruit-Derived Ingredients as Used in Cosmetics. Tentative Report for Public Comment.2015.